A Prospective Study of Oxidative Stress Biomarkers in Autistic Disorders

David A Geier, Janet K Kern, Mark R Geier

Abstract


The aim of this study was to evaluate oxidative stress (OS) biomarkers in a prospective, blinded cohort study of participants diagnosed with autism spectrum disorders (ASDs). OS biomarkers, including: blood glutathione (GSH), urine lipid peroxide, blood superoxidase dismutase (SOD), and blood GSH peroxidase (GPx) among participants diagnosed with ASDs (n=28) were evaluated in comparison to laboratory provided reference ranges. Testing was conducted using Genova Diagnostics (CLIA-approved). Participants diagnosed with ASDs had significantly (p

Keywords


heavy metal; metabolic endophenotype; sulfation; sulfur

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ISSN 1832-7931
Swinburne University of Technology